IUBMB Enzyme Nomenclature


Accepted name: 23S rRNA (uracil747-C5)-methyltransferase

Reaction: S-adenosyl-L-methionine + uracil747 in 23S rRNA = S-adenosyl-L-homocysteine + 5-methyluracil747 in 23S rRNA

Other name(s): YbjF; RumB; RNA uridine methyltransferase B

Systematic name: S-adenosyl-L-methionine:23S rRNA (uracil747-C5)-methyltransferase

Comments: The enzyme specifically methylates uracil747 at C5 in 23S rRNA.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Madsen, C.T., Mengel-Jorgensen, J., Kirpekar, F. and Douthwaite, S. Identifying the methyltransferases for m5U747 and m5U1939 in 23S rRNA using MALDI mass spectrometry. Nucleic Acids Res. 31 (2003) 4738-4746. [PMID: 12907714]

[EC created 2010]

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