IUBMB Enzyme Nomenclature


Accepted name: naringenin 7-O-methyltransferase

Reaction: S-adenosyl-L-methionine + (2S)-naringenin = S-adenosyl-L-homocysteine + (2S)-sakuranetin

For diagram of reaction, click here

Glossary: naringenin = (2S)-5,7,4'-trihydroxyflavanone = (2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-2,3-dihydrochromen-4-one
sakuranetin = (2S)-5,4'-dihydroxy-7-methoxyflavanone = (2S)-5-hydroxy-2-(4-hydroxyphenyl)-7-methoxy-2,3-dihydrochromen-4-one

Other name(s): NOMT

Systematic name: S-adenosyl-L-methionine:(2S)-5,7,4'-trihydroxyflavanone 7-O-methyltransferase

Comments: The enzyme is involved in the biosynthesis of the sakuranetin, an inducible defense mechanism of Oryza sativa against pathogen attack.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Rakwal, R., Agrawal, G.K., Yonekura, M. and Kodama, O. Naringenin 7-O-methyltransferase involved in the biosynthesis of the flavanone phytoalexin sakuranetin from rice (Oryza sativa L.). Plant Sci. 155 (2000) 213-221. [PMID: 10814825]

[EC created 2011]

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