IUBMB Enzyme Nomenclature

EC 2.1.1.313

Accepted name: 25S rRNA (uracil2634-N3)-methyltransferase

Reaction: S-adenosyl-L-methionine + uracil2634 in 25S rRNA = S-adenosyl-L-homocysteine + N3-methyluracil2634 in 25S rRNA

Other name(s): BMT5

Systematic name: S-adenosyl-L-methionine:tRNA (uracil2634-N3)-methyltransferase

Comments: The enzyme, described from the yeast Saccharomyces cerevisiae, is involved in ribosome biogenesis.

References:

1. Sharma, S., Yang, J., Duttmann, S., Watzinger, P., Kotter, P. and Entian, K.D. Identification of novel methyltransferases, Bmt5 and Bmt6, responsible for the m3U methylations of 25S rRNA in Saccharomyces cerevisiae. Nucleic Acids Res. 42 (2014) 3246-3260. [PMID: 24335083]

[EC 2.1.1.313 created 2014]


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