IUBMB Enzyme Nomenclature

EC 2.1.1.399

Accepted name: resveratrol 4'-O-methyltransferase

Reaction: S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 4'-O-methyl-trans-resveratrol

Other name(s): AcOMT1

Systematic name: S-adenosyl-L-methionine:trans-resveratrol 4'-O-methyltransferase

Comments: The enzyme occurs in the roots and leaves of the plant Acorus calamus (sweet flag). In additon to trans-reveratrol it is active toward isorhapontigenin and shows slight activities toward piceatannol, oxyresveratrol, and pinostilbene.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Koeduka, T., Hatada, M., Suzuki, H., Suzuki, S. and Matsui, K. Molecular cloning and functional characterization of an O-methyltransferase catalyzing 4'-O-methylation of resveratrol in Acorus calamus. J. Biosci. Bioeng. 127 (2019) 539-543. [PMID: 30471982]

[EC 2.1.1.399 created 2024]


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