IUBMB Enzyme Nomenclature

EC 2.1.1.401

Accepted name: nicotinate methyltransferase

Reaction: S-adenosyl-L-methionine + nicotinate = S-adenosyl-L-homocysteine + methyl nicotinate

Glossary: methyl nicotinate = nicitinic acid methyl ester

Other name(s): NaMT1

Systematic name: S-adenosyl-L-methionine:nicotinate O-methyltransferase

Comments: The enzyme has been charcterized from the plant Arabidopsis thaliana. The product, methyl nicotinate, is involved in the transport of nicotinate to different parts of the plant.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:

References:

1. Wu, R., Zhang, F., Liu, L., Li, W., Pichersky, E. and Wang, G. MeNA, controlled by reversible methylation of nicotinate, is an NAD precursor that undergoes long-distance transport in Arabidopsis. Mol. Plant 11 (2018) 1264-1277. [PMID: 30055263]

[EC 2.1.1.401 created 2025]


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