IUBMB Enzyme Nomenclature


Accepted name: betaine—homocysteine S-methyltransferase

Reaction: trimethylammonioacetate + L-homocysteine = dimethylglycine + L-methionine

Other name(s): betaine-homocysteine methyltransferase; betaine-homocysteine transmethylase

Systematic name: trimethylammonioacetate:L-homocysteine S-methyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9029-78-1


1. Klee, W.A., Richards, H.H. and Cantoni, G.L. The synthesis of methionine by enzymic transmethylation. VII. Existence of two separate homocysteine methylpherases on mammalian liver. Biochim. Biophys. Acta 54 (1961) 157-164.

[EC created 1961]

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