IUBMB Enzyme Nomenclature


Accepted name: tRNA (adenine-N6-)-methyltransferase

Reaction: S-adenosyl-L-methionine + tRNA = S-adenosyl-L-homocysteine + tRNA containing N6-methyladenine

Systematic name: S-adenosyl-L-methionine:tRNA (adenine-N6-)-methyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9014-53-3


1. Mandel, R., Hacker, B. and Maag, T.A. Altered transfer RNA methylase patterns in Marek's disease tumors. Cancer Res. 31 (1971) 613-616. [PMID: 4996578]

2. Mittelman, A., Hall, R.H., Yohn, D.S. and Grace, J.T. The in vitro soluble RNA methylase activity of SV40-induced hamster tumors. Cancer Res. 27 (1967) 1409-1414. [PMID: 4292682]

3. Sharma, O.K. Differences in the transfer RNA methyltransferases from normal rat liver and Novikoff hepatoma. Biochim. Biophys. Acta 299 (1973) 415-427. [PMID: 4349332]

[EC created 1981]

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