IUBMB Enzyme Nomenclature


Accepted name: histamine N-methyltransferase

Reaction: S-adenosyl-L-methionine + histamine = S-adenosyl-L-homocysteine + Nτ-methylhistamine

Other name(s): histamine 1-methyltransferase; histamine methyltransferase; histamine-methylating enzyme; imidazolemethyltransferase; S-adenosylmethionine-histamine N-methyltransferase

Systematic name: S-adenosyl-L-methionine:histamine N-tele-methyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9029-80-5


1. Brown, D.D., Tomchick, R. and Axelrod, J. The distribution and properties of a histamine-methylating enzyme. J. Biol. Chem. 234 (1959) 2948-2950.

[EC created 1965]

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