IUBMB Enzyme Nomenclature


Accepted name: alkylglycerophosphate 2-O-acetyltransferase

Reaction: acetyl-CoA + 1-alkyl-sn-glycero-3-phosphate = CoA + 1-alkyl-2-acetyl-sn-glycero-3-phosphate

Other name(s): alkyllyso-GP:acetyl-CoA acetyltransferase

Systematic name: acetyl-CoA:1-alkyl-sn-glycero-3-phosphate 2-O-acetyltransferase

Comments: Involved in the biosynthesis of thrombocyte activating factor in animal tissues.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 76773-96-1 (not distinguishable from EC 1-alkylglycerophosphocholine O-acetyltransferase in Chemical Abstracts)


1. Lee, T.-C., Malone, B. and Snyder, F. A new de novo pathway for the formation of 1-alkyl-2-acetyl-sn-glycerols, precursors of platelet activating factor. Biochemical characterization of 1-alkyl-2-lyso-sn-glycero-3-P:acetyl-CoA acetyltransferase in rat spleen. J. Biol. Chem. 261 (1986) 5373-5377. [PMID: 3007498]

[EC created 1989]

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