IUBMB Enzyme Nomenclature


Accepted name: 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Reaction: succinyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H2O = CoA + N-succinyl-L-2-amino-6-oxoheptanedioate

For diagram click here.

dipicolinate = pyridine-2,6-dicarboxylate

Other name(s): tetrahydropicolinate succinylase; tetrahydrodipicolinate N-succinyltransferase; tetrahydrodipicolinate succinyltransferase; succinyl-CoA:tetrahydrodipicolinate N-succinyltransferase; succinyl-CoA:2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Systematic name: succinyl-CoA:(S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase

Comments: Involved in the biosynthesis of lysine in bacteria (including cyanobacteria) and higher plants. The 1992 edition of the Enzyme List erroneously gave the name 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase to this enzyme.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 88086-34-4


1. Simms, S.A., Voige, W.H. and Gilvarg, C. Purification and characterization of succinyl-CoA: tetrahydrodipicolinate N-succinyltransferase from Escherichia coli. J. Biol. Chem. 259 (1984) 2734-2741. [PMID: 6365916]

[EC created 1989, modified 2001]

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