IUBMB Enzyme Nomenclature


Accepted name: carnitine O-octanoyltransferase

Reaction: octanoyl-CoA + L-carnitine = CoA + L-octanoylcarnitine

Other name(s): medium-chain/long-chain carnitine acyltransferase; carnitine medium-chain acyltransferase; easily solubilized mitochondrial carnitine palmitoyltransferase; overt mitochondrial carnitine palmitoyltransferase

Systematic name: octanoyl-CoA:L-carnitine O-octanoyltransferase

Comments: Acts on a range of acyl-CoAs, with optimal activity with C6 or C8 acyl groups. cf. EC (carnitine O-acetyltransferase) and EC (carnitine O-palmitoyltransferase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 39369-19-2


1. Farrell, S.O., Fiol, C.J., Reddy, J.K. and Bieber, L.L. Properties of purified carnitine acyltransferases of mouse liver peroxisomes. J. Biol. Chem. 259 (1984) 13089-13095. [PMID: 6436243]

2. Healy, M.J., Kerner, J. and Bieber, L.L. Enzymes of carnitine acylation. Is overt carnitine palmitoyltransferase of liver peroxisomal carnitine octanoyltransferase? Biochem. J. 249 (1988) 231-237. [PMID: 3342008]

3. Miyazawa, S., Ozasa, H., Osumi, T. and Hashimoto, T. Purification and properties of carnitine octanoyltransferase and carnitine palmitoyltransferase from rat liver. J. Biochem. (Tokyo) 94 (1983) 529-542. [PMID: 6630173]

[EC created 1992]

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