IUBMB Enzyme Nomenclature

EC 2.3.1.172

Accepted name: anthocyanin 5-O-glucoside 6'''-O-malonyltransferase

Reaction: malonyl-CoA + pelargonidin 3-O-(6-caffeoyl-β-D-glucoside) 5-O-β-D-glucoside = CoA + 4'''-demalonylsalvianin

For diagram click here.

Glossary: salvianin = pelargonidin 3-O-(6-caffeoyl-β-D-glucoside) 5-O-(4,6-di-O-malonyl-β-D-glucoside)
4'''-demalonylsalvianin = pelargonidin 3-O-(6-caffeoyl-β-D-glucoside) 5-O-(6-O-malonyl-β-D-glucoside)
pelargonidin = 3,4′,5,7-tetrahydroxyflavylium

Other Name(s): Ss5MaT1

Systematic name: malonyl-CoA:pelargonidin-3-O-(6-caffeoyl-β-D-glucoside)-5-O-β-D-glucoside 6'''-O-malonyltransferase

Comments: Specific for the penultimate step in salvianin biosynthesis. The enzyme also catalyses the malonylation of shisonin to malonylshisonin [cyanidin 3-O-(6"-O-p-coumaryl-β-D-glucoside)-5-(6'''-O-malonyl-β-D-glucoside)]. The compounds 4'''-demalonylsalvianin, salvianin, pelargonidin 3,5-diglucoside and delphinidin 3,5-diglucoside cannot act as substrates.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 380229-66-3

References:

1. Suzuki, H., Nakayama, T., Yonekura-Sakakibara, K., Fukui, Y., Nakamura, N., Nakao, M., Tanaka, Y., Yamaguchi, M.A., Kusumi, T. and Nishino, T. Malonyl-CoA:anthocyanin 5-O-glucoside-6'''-O-malonyltransferase from scarlet sage (Salvia splendens) flowers. J. Biol. Chem. 276 (2001) 49013-49019. [PMID: 11598135]

[EC 2.3.1.172 created 2004]


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