IUBMB Enzyme Nomenclature


Accepted name: ethanol O-acetyltransferase

Reaction: ethanol + acetyl-CoA = ethyl acetate + CoA

Other name(s): eat1 (gene name); ethanol acetyltransferase

Systematic name: acetyl-CoA:ethanol O-acetyltransferase

Comments: The enzyme, characterized from the yeast Wickerhamomyces anomalus, is responsible for most ethyl acetate synthesis in known ethyl acetate-producing yeasts. It is only distantly related to enzymes classified as EC, alcohol O-acetyltransferase. The enzyme also possesses thioesterase and esterase activities, which are inhibited by high ethanol concentrations.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Kruis, A.J., Levisson, M., Mars, A.E., van der Ploeg, M., Garces Daza, F., Ellena, V., Kengen, S.WM., van der Oost, J. and Weusthuis, R.A. Ethyl acetate production by the elusive alcohol acetyltransferase from yeast. Metab. Eng. 41 (2017) 92-101. [PMID: 28356220]

[EC created 2018]

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