IUBMB Enzyme Nomenclature


Accepted name: chloramphenicol O-acetyltransferase

Reaction: acetyl-CoA + chloramphenicol = CoA + chloramphenicol 3-acetate

Other name(s): chloramphenicol acetyltransferase; chloramphenicol acetylase; chloramphenicol transacetylase; CAT I; CAT II; CAT III

Systematic name: acetyl-CoA:chloramphenicol 3-O-acetyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9040-07-7


1. Shaw, W.V. The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli. J. Biol. Chem. 242 (1967) 687-693. [PMID: 5335032]

2. Shaw, W.V. and Brodsky, R.F. Characterization of chloramphenicol acetyltransferase from chloramphenicol-resistant Staphylococcus aureus. J. Bacteriol. 95 (1968) 28-36. [PMID: 4965980]

[EC created 1972]

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