Reaction: benzoyl-CoA + ecgonine methyl ester = CoA + cocaine
For diagram of reaction click here.
Systematic name: benzoyl-CoA:ecgonine methyl ester O-benzoyltransferase
Comments: Isolated from the plant Erythoxylum coca. Cinnamoyl-CoA can substitute for benzoyl-CoA.
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Schmidt, G.W., Jirschitzka, J., Porta, T., Reichelt, M., Luck, K., Torre, J.C., Dolke, F., Varesio, E., Hopfgartner, G., Gershenzon, J. and D'Auria, J.C. The last step in cocaine biosynthesis is catalyzed by a BAHD acyltransferase. Plant Physiol. 167 (2015) 89-101. [PMID: 25406120]