IUBMB Enzyme Nomenclature

EC 2.3.1.66

Accepted name: leucine N-acetyltransferase

Reaction: acetyl-CoA + L-leucine = CoA + N-acetyl-L-leucine

Other name(s): leucine acetyltransferase

Systematic name: acetyl-CoA:L-leucine N-acetyltransferase

Comments: Propanoyl-CoA can act as a donor, but more slowly. L-Arginine, L-valine, L-phenylalanine and peptides containing L-leucine can act as acceptors.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 75496-56-9

References:

1. Suzukake, S., Hayashi, H., Hori, M. and Umezawa, H. Biosnthesis of leupeptin III. Isolation and properties of an enzyme synthesizing acetyl-L-leucine. J. Antibiot. 33 (1982) 857-862.

[EC 2.3.1.66 created 1983]


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