IUBMB Enzyme Nomenclature


Accepted name: L-ornithine Nα-acyltransferase

Reaction: L-ornithine + a (3R)-3-hydroxyacyl-[acyl-carrier protein] = a lyso-ornithine lipid + a holo-[acyl-carrier protein]

Glossary: a lyso-ornithine lipid = an Nα-[(3R)-hydroxy-acyl]-L-ornithine

Other name(s): olsB (gene name)

Systematic name: L-ornithine Nα-(3R)-3-hydroxy-acyltransferase

Comments: The enzyme, found in bacteria, catalyses the first step in the biosynthesis of ornithine lipids.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Gao, J.L., Weissenmayer, B., Taylor, A.M., Thomas-Oates, J., Lopez-Lara, I.M. and Geiger, O. Identification of a gene required for the formation of lyso-ornithine lipid, an intermediate in the biosynthesis of ornithine-containing lipids. Mol. Microbiol. 53 (2004) 1757-1770. [PMID: 15341653]

2. Vences-Guzman, M.A., Guan, Z., Bermudez-Barrientos, J.R., Geiger, O. and Sohlenkamp, C. Agrobacteria lacking ornithine lipids induce more rapid tumour formation. Environ Microbiol 15 (2013) 895-906. [PMID: 22958119]

[EC created 2017]

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