IUBMB Enzyme Nomenclature


Accepted name: α,α-trehalose-phosphate synthase (UDP-forming)

Reaction: UDP-α-D-glucose + D-glucose 6-phosphate = UDP + α,α-trehalose 6-phosphate

Other name(s): UDP-glucose—glucose-phosphate glucosyltransferase; trehalosephosphate-UDP glucosyltransferase; UDP-glucose-glucose-phosphate glucosyltransferase; α,α-trehalose phosphate synthase (UDP-forming); phosphotrehalose-uridine diphosphate transglucosylase; trehalose 6-phosphate synthase; trehalose 6-phosphate synthetase; trehalose phosphate synthase; trehalose phosphate synthetase; trehalose phosphate-uridine diphosphate glucosyltransferase; trehalose-P synthetase; transglucosylase; uridine diphosphoglucose phosphate glucosyltransferase

Systematic name: UDP-α-D-glucose:D-glucose-6-phosphate 1-α-D-glucosyltransferase (configuration-retaining)

Comments: See also EC [α,α-trehalose-phosphate synthase (GDP-forming)].

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9030-07-3


1. Cabib, E. and Leloir, L.F. The biosynthesis of trehalose phosphate. J. Biol. Chem. 231 (1958) 259-275.

2. Candy, D.J. and Kilby, B.A. The biosynthesis of trehalose in the locust fat body. Biochem. J. 78 (1961) 531-536.

3. Lornitzo, F.A. and Goldman, D.S. Purification and properties of the transglucosylase inhibitor of Mycobacterium tuberculosis. J. Biol. Chem. 239 (1964) 2730-2734.

4. Murphy, T.A. and Wyatt, G.R. The enzymes of glycogen and trehalose synthesis in silk moth fat body. J. Biol. Chem. 240 (1965) 1500-1508.

[EC created 1961]

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