IUBMB Enzyme Nomenclature


Accepted name: chitin synthase

Reaction: UDP-N-acetyl-α-D-glucosamine + [(1→4)-N-acetyl-β-D-glucosaminyl]n = UDP + [(1→4)-N-acetyl-β-D-glucosaminyl]n+1

Glossary: chitin = [(1→4)-N-acetyl-β-D-glucosaminyl]n

Other name(s): chitin-UDP N-acetylglucosaminyltransferase; chitin-uridine diphosphate acetylglucosaminyltransferase; chitin synthetase; trans-N-acetylglucosaminosylase; UDP-N-acetyl-D-glucosamine:chitin 4-β-N-acetylglucosaminyl-transferase; UDP-N-acetyl-α-D-glucosamine:chitin 4-β-N-acetylglucosaminyltransferase

Systematic name: UDP-N-acetyl-α-D-glucosamine:chitin 4-β-N-acetylglucosaminyltransferase (configuration-inverting)

Comments: Converts UDP-N-acetyl-α-D-glucosamine into chitin and UDP.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9030-18-6


1. Glaser, L. and Brown, D.H. The synthesis of chitin in cell-free extracts of Neurospora crassa. J. Biol. Chem. 228 (1957) 729-742.

2. Sburlati, A. and Cabib, E. Chitin synthetase 2, a presumptive participant in septum formation in Saccharomyces cerevisiae. J. Biol. Chem. 261 (1986) 15147-15152. [PMID: 2945823]

[EC created 1961]

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