IUBMB Enzyme Nomenclature

EC 2.4.1.219

Accepted name: vomilenine glucosyltransferase

Reaction: UDP-glucose + vomilenine = UDP + raucaffricine

For diagram click here.

Other name(s): UDPG:vomilenine 21-β-D-glucosyltransferase

Systematic name: UDP-glucose:vomilenine 21-O-β-D-glucosyltransferase

Comments: The indole alkaloid raucaffricine accumulates during the culture of Rauvolfia cell suspensions.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number:

References:

1. Warzecha, H., Obitz, P. and Stöckigt, J. Purification, partial amino acid sequence and structure of the product of raucaffricine-O-β-D-glucosidase from plant cell cultures of Rauwolfia serpentina. Phytochemistry 50 (1999) 1099-1109. [PMID: 10234858]

2. Warzecha, H., Gerasimenko, I., Kutchan, T.M. and Stöckigt, J. Molecular cloning and functional bacterial expression of a plant glucosidase specifically involved in alkaloid biosynthesis. Phytochemistry 54 (2000) 657-666. [PMID: 10975500]

3. Ruyter, C.M., and Stöckigt, J. Enzymatic formation of raucaffricine, the major indole alkaloid of Rauwolfia serpentina cell-suspension cultures. Helv. Chim. Acta 74 (1991) 1707-1712.

[EC 2.4.1.219 created 2002]


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