Reaction: Transfers a segment of a (1→4)-α-D-glucan to a new position in an acceptor, which may be glucose or a (1→4)-α-D-glucan
Other name(s): disproportionating enzyme; dextrin glycosyltransferase; D-enzyme; debranching enzyme maltodextrin glycosyltransferase; amylomaltase; dextrin transglycosylase; 1,4-α-D-glucan:1,4-α-D-glucan 4-α-D-glycosyltransferase
Systematic name: (1→4)-α-D-glucan:(1→4)-α-D-glucan 4-α-D-glycosyltransferase
Comments: This entry covers the former separate entry for EC 2.4.1.3 (amylomaltase). The plant enzyme has been termed D-enzyme. An enzymic activity of this nature forms part of the mammalian and yeast glycogen debranching system (see EC 3.2.1.33 amylo-α-1,6-glucosidase).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9032-09-1
References:
1. Hehre, E.J. Enzymic synthesis of polysaccharides: a biological type of polymerization. Adv. Enzymol. Relat. Subj. Biochem. 11 (1951) 297-337.
2. Lukomskaya, I.S. Synthesis of oligosaccharides with α-1,6-bonds by enzyme preparations from liver and muscle. Dokl. Akad. Nauk S.S.S.R. 129 (1959) 1172-1175. [Russian]
3. Pazur, J.H. and Okada, S. The isolation and mode of action of a bacterial glucanosyltransferase. J. Biol. Chem. 243 (1968) 4732-4738. [PMID: 4972097]
4. Walker, G.J. and Whelan, W.J. Synthesis of amylose by potato D-enzyme. Nature 183 (1959) 46 only. [PMID: 13622683]
5. Whelan, W.H. Enzymic explorations of the structures of starch and glycogen. Biochem. J. 122 (1971) 609-622. [PMID: 5001952]