IUBMB Enzyme Nomenclature


Accepted name: UDP-GlcNAc:ribostamycin N-acetylglucosaminyltransferase

Reaction: UDP-N-acetyl-α-D-glucosamine + ribostamycin = UDP + 2′′′-acetyl-6′′′-hydroxyneomycin C

Other name(s): neoK (gene name)

Systematic name: UDP-N-acetyl-α-D-glucosamine:ribostamycin N-acetylglucosaminyltransferase

Comments: Involved in biosynthesis of the aminoglycoside antibiotic neomycin. Requires a divalent metal ion, optimally Mg2+, Mn2+ or Co2+.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Yokoyama, K., Yamamoto, Y., Kudo, F. and Eguchi, T. Involvement of two distinct N-acetylglucosaminyltransferases and a dual-function deacetylase in neomycin biosynthesis. ChemBioChem. 9 (2008) 865-869. [PMID: 18311744]

[EC created 2012]

Return to EC 2.4.1 home page
Return to EC 2.4 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page