Reaction: (1) UDP-α-D-glucose + naringenin chalcone = UDP + 2',4,4',6'-tetrahydroxychalcone 4'-O-β-D-glucoside
(2) UDP-α-D-glucose + 2',3,4,4',6'-pentahydroxychalcone = UDP + 2',3,4,4',6'-pentahydroxychalcone 4'-O-β-D-glucoside
For diagram of reaction click here.
Glossary: 2',4,4',6'-tetrahydroxychalcone = 3-(4-hydroxyphemyl)-1-(2,4,6-trihydroxyphenyl)prop-2-en-1-one
Other name(s): 4’CGT
Systematic name: UDP-α-D-glucose:2',4,4',6'-tetrahydroxychalcone 4'-O-β-D-glucosyltransferase
Comments: Isolated from the plant Antirrhinum majus (snapdragon). Involved in the biosynthesis of aurones, plant flavonoids that provide yellow color to the flowers.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
References:
1. Ono, E., Fukuchi-Mizutani, M., Nakamura, N., Fukui, Y., Yonekura-Sakakibara, K., Yamaguchi, M., Nakayama, T., Tanaka, T., Kusumi, T. and Tanaka, Y. Yellow flowers generated by expression of the aurone biosynthetic pathway. Proc. Natl. Acad. Sci. USA 103 (2006) 11075-11080. [PMID: 16832053]