Reaction: UDP-α-D-glucose + an anthocyanidin 3-O-β-D-glucoside = UDP + an anthocyanidin 3,5-di-O-β-D-glucoside
For diagram of reaction click here.
Other name(s): UDP-glucose:anthocyanin 5-O-glucosyltransferase
Systematic name: UDP-α-D-glucose:anthocyanidin-3-O-β-D-glucoside 5-O-glucosyltransferase
Comments: Isolated from the plants Perilla frutescens var. crispa, Verbena hybrida , Dahlia variabilis  and Gentiana triflora (clustered gentian) . It will also act on anthocyanidin 3-O-(6-O-malonylglucoside)  and is much less active with hydroxycinnamoylglucose derivatives . There is no activity in the absence of the 3-O-glucoside group.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:
1. Yamazaki, M., Gong, Z., Fukuchi-Mizutani, M., Fukui, Y., Tanaka, Y., Kusumi, T. and Saito, K. Molecular cloning and biochemical characterization of a novel anthocyanin 5-O-glucosyltransferase by mRNA differential display for plant forms regarding anthocyanin. J. Biol. Chem. 274 (1999) 7405-7411. [PMID: 10066805]
2. Ogata, J., Sakamoto, T., Yamaguchi, M., Kawanobu, S., Yoshitama, K. Isolation and characterization of anthocyanin 5-O-glucosyltransferase from flowers of Dahlia variabilis. J. Plant Physiol. 158 (2001) 709-714.
3. Nakatsuka, T., Sato, K., Takahashi, H., Yamamura, S. and Nishihara, M. Cloning and characterization of the UDP-glucose:anthocyanin 5-O-glucosyltransferase gene from blue-flowered gentian. J. Exp. Bot. 59 (2008) 1241-1252. [PMID: 18375606]