IUBMB Enzyme Nomenclature


Accepted name: erythronolide mycarosyltransferase

Reaction: dTDP-β-L-mycarose + erythronolide B = dTDP + 3-α-L-mycarosylerythronolide B

For diagram of reaction click here.

Glossary: dTDP-β-L-mycarose = dTDP-2,6-dideoxy-3-C-methyl-β-L-ribo-hexose
L-mycarose = 2,6-dideoxy-3-C-methyl-L-ribo-hexose

Other name(s): EryBV

Systematic name: dTDP-β-L-mycarose:erythronolide B L-mycarosyltransferase

Comments: Isolated from the bacterium Saccharopolyspora erythraea. The enzyme is involved in the biosynthesis of the antibiotic erythromycin.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Zhang, C., Fu, Q., Albermann, C., Li, L. and Thorson, J.S. The in vitro characterization of the erythronolide mycarosyltransferase EryBV and its utility in macrolide diversification. Chembiochem 8 (2007) 385-390. [PMID: 17262863]

[EC created 2014]

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