Reaction: (R)-phenyllactyl-β-D-glucose + tropine = D-glucose + littorine
For diagram of reaction click here.
Glossary: tropine = (3-endo)-8-methyl-8-azabicyclo[3.2.1]octan-3-ol
littorine = 8-methyl-8-azabicyclo[3.2.1]oct-3-yl (2R)-2-hydroxy-3-phenylpropanoate
Other name(s): LS (gene name)
Systematic name: (R)-phenyllactyl-β-D-glucose:tropine O-D-glucosyltransferase (littorine forming)
Comments: Isolated from the plant Atropa belladonna (deadly nightshade). Involved in the biosynthesis of the alkaloid L-hyoscyamine (S-atropine).
Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:
References:
1. Qiu, F., Zeng, J., Wang, J., Huang, J.P., Zhou, W., Yang, C., Lan, X., Chen, M., Huang, S.X., Kai, G. and Liao, Z. Functional genomics analysis reveals two novel genes required for littorine biosynthesis. New Phytol. 225 (2020) 1906-1914. [PMID: 31705812]