Reaction: UDP-glucose + a flavonol = UDP + a flavonol 3-O-β-D-glucoside
See diagram for reaction on kaempferol or quercetin.
Other name(s): GTI; uridine diphosphoglucose-flavonol 3-O-glucosyltransferase; UDP-glucose:flavonol 3-O-glucosyltransferase; UDPG:flavonoid-3-O-glucosyltransferase
Systematic name: UDP-glucose:flavonol 3-O-D-glucosyltransferase
Comments: Acts on a variety of flavonols, including quercetin and quercetin 7-O-glucoside. Different from EC 18.104.22.168 (flavone 7-O-β-glucosyltransferase).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 50812-18-5
1. Kleinehollenhorst, G., Behrens, H., Pegels, G., Srunk, N. and Wiermann, R. Formation of flavonol 3-O-diglycosides and flavonol 3-O-triglycosides by enzyme extracts from anthers of Tulipa cv apeldoorn - characterization and activity of 3 different O-glycosyltransferases during anther development. Z. Natursforsch. C: Biosci. 37 (1982) 587-599.
2. Sutter, A. and Grisebach, H. UDP-glucose: flavonol 3-O-glucosyltransferase from cell suspension cultures of parsley. Biochim. Biophys. Acta 309 (1973) 289-295. [PMID: 4731963]