IUBMB Enzyme Nomenclature


Accepted name: fumigaclavine A dimethylallyltransferase

Reaction: fumigaclavine A + dimethylallyl diphosphate = fumigaclavine C + diphosphate

For diagram of reaction click here.

Glossary: fumigaclavine A = 6,8β-dimethylergolin-9β-yl acetate
fumigaclavine C = 2-(2-methylbut-3-en-2-yl)-6,8β-dimethylergolin-9β-yl acetate

Other name(s): FgaPT1

Systematic name: dimethylallyl-diphosphate:fumigaclavine A dimethylallyltransferase

Comments: Fumigaclavine C is an ergot alkaloid produced by some fungi of the Trichocomaceae family. Activity does not require any metal ions.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:


1. Unsöld, I.A. and Li, S.M. Reverse prenyltransferase in the biosynthesis of fumigaclavine C in Aspergillus fumigatus: gene expression, purification, and characterization of fumigaclavine C synthase FGAPT1. ChemBioChem. 7 (2006) 158-164. [PMID: 16397874]

[EC created 2012]

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