IUBMB Enzyme Nomenclature


Accepted name: chlorophyll synthase

Reaction: chlorophyllide a + phytyl diphosphate = chlorophyll a + diphosphate

For diagram of reaction click here or click here.

Systematic name: chlorophyllide-a:phytyl-diphosphate phytyltransferase

Comments: Requires Mg2+. The enzyme is modified by binding of the first substrate, phytyl diphosphate, before reaction of the modified enzyme with the second substrate, chlorophyllide a, can occur. The reaction also occurs when phytyl diphosphate is replaced by geranylgeranyl diphosphate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9077-08-1


1. Schmid, H.C., Rassadina, V., Oster, U., Schoch, S. and Rüdiger, W. Pre-loading of chlorophyll synthase with tetraprenyl diphosphate is an obligatory step in chlorophyll biosynthesis. Biol. Chem. 383 (2002) 1769-1778. [PMID: 12530542]

2. Oster, U., Bauer, C.E. and Rüdiger, W. Characterization of chlorophyll a and bacteriochlorophyll a synthases by heterologous expression in Escherichia coli. J. Biol. Chem. 272 (1997) 9671-9676. [PMID: 9092496]

3. Rüdiger, W., Benz, J. and Guthoff. C. Detection and partial characterization of activity of chlorophyll synthetase in etioplast membranes. Eur. J. Biochem. 109 (1980) 193-200. [PMID: 7408876]

[EC created 2003]

Return to EC 2.5.1 home page
Return to EC 2.5 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page