IUBMB Enzyme Nomenclature

EC 2.5.1.63

Accepted name: adenosyl-fluoride synthase

Reaction: S-adenosyl-L-methionine + fluoride = 5'-deoxy-5'-fluoroadenosine + L-methionine

Other name(s): fluorinase

Systematic name: S-adenosyl-L-methionine:fluoride adenosyltransferase

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 438583-16-5

References:

1. O'Hagan, D., Schaffrath, C., Cobb, S.L., Hamilton, J.T. and Murphy, C.D. Biosynthesis of an organofluorine molecule. Nature 416 (2002) 279 only. [PMID: 11907567]

2. Dong, C., Huang, F., Deng, H., Schaffrath, C., Specner, J.B., O'Hagan, D. and Naismith, J.H. Crystal structure and mechanism of a bacterial fluorinating enzyme. Nature 427 (2004) 561-565. [PMID: 14765200]

[EC 2.5.1.63 created 2003]


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