IUBMB Enzyme Nomenclature

EC 2.6.1.116

Accepted name: 6-aminohexanoate aminotransferase

Reaction: 6-aminohexanoate + 2-oxoglutarate = 6-oxohexanoate + L-glutamate

Other name(s): nylD (gene name)

Systematic name: 6-aminohexanoate:2-oxogutarate aminotransferase

Comments: The enzyme, characterized from the bacterium Arthrobacter sp. KI72, participates in the degradation of nylon-6. Glyoxylate can serve as an alternative amino group acceptor with similar efficiency.

References:

1. Takehara, I., Fujii, T., Tanimoto, Y., Kato, D.I., Takeo, M. and Negoro, S. Metabolic pathway of 6-aminohexanoate in the nylon oligomer-degrading bacterium Arthrobacter sp. KI72: identification of the enzymes responsible for the conversion of 6-aminohexanoate to adipate. Appl. Microbiol. Biotechnol. 102 (2018) 801-814. [PMID: 29188330]

[EC 2.6.1.116 created 2019]


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