IUBMB Enzyme Nomenclature


Accepted name: β-alanine—2-oxoglutarate transaminase

Reaction: β-alanine + 2-oxoglutarate = 3-oxopropanoate + L-glutamate

For diagram of reaction, click here

Other name(s): pydD (gene name); β-alanine aminotransferase

Systematic name: β-alanine:2-oxoglutarate aminotransferase

Comments: The enzyme, found in many Gram-positive bacteria, participates in the reductive degradation of pyrimidines. In eukaryotes this activity is catalysed by EC, 4-aminobutyrate—2-oxoglutarate transaminase.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Fujimoto, S., Mizutani, N., Mizota, C. and Tamaki, N. The level of β-alanine aminotransferase activity in regenerating and differentiating rat liver. Biochim. Biophys. Acta 882 (1986) 106-112. [PMID: 3085724]

2. Yin, J., Wei, Y., Liu, D., Hu, Y., Lu, Q., Ang, E.L., Zhao, H. and Zhang, Y. An extended bacterial reductive pyrimidine degradation pathway that enables nitrogen release from β-alanine. J. Biol. Chem. 294 (2019) 15662-15671. [PMID: 31455636]

[EC created 2021]

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