Reaction: L-ornithine + a 2-oxo carboxylate = L-glutamate 5-semialdehyde + an L-amino acid
Other name(s): ornithine δ-transaminase; L-ornithine:α-ketoglutarate δ-aminotransferase; OAT; L-ornithine 5-aminotransferase; L-ornithine aminotransferase; ornithine 5-aminotransferase; ornithine transaminase; ornithine-α-ketoglutarate aminotransferase; ornithine-2-oxoacid aminotransferase; ornithine-keto acid aminotransferase; ornithine-keto acid transaminase; ornithine-ketoglutarate aminotransferase; ornithine-oxo acid aminotransferase; ornithine:α-oxoglutarate transaminase; ornithine—oxo-acid transaminase
Systematic name: L-ornithine:2-oxo-acid aminotransferase
Comments: A pyridoxal-phosphate protein.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9030-42-6
References:
1. Fincham, J.R.S. Ornithine transaminase in Neurospora and its relation to the biosynthesis of proline. Biochem. J. 53 (1953) 313-320.
2. Katunuma, N., Matsuda, Y. and Tomino, I. Studies on ornithine-ketoacid transaminase. I. Purification and properties.J. Biochem. (Tokyo) 56 (1964) 499-503.
3. Meister, A. Enzymatic transamination reactions involving arginine and ornithine. J. Biol. Chem. 206 (1954) 587-596.
4. Peraino, C., Bunville, L.G. and Tahmisian, T.N. Chemical, physical, and morphological properties of ornithine aminotransferase from rat liver. J. Biol. Chem. 244 (1969) 2241-2249. [PMID: 5783831]
5. Quastel, J.H. and Witty, R. Ornithine transaminase. Nature 167 (1951) 556 only.
6. Strecker, H.J. Purification and properties of rat liver ornithine δ-transaminase. J. Biol. Chem. 240 (1965) 1225-1230.