IUBMB Enzyme Nomenclature

EC 2.6.1.15

Accepted name: glutamine—pyruvate transaminase

Reaction: L-glutamine + pyruvate = 2-oxoglutaramate + L-alanine

For diagram click here (mechanism).

Other name(s): glutaminase II; L-glutamine transaminase L; glutamine-oxo-acid transaminase

glutamine transaminase L; γ-glutaminyltransferase; glutamine transaminase; glutamine-α-keto acid transaminase; glutamine-keto acid aminotransferase; glutamine-α-keto acid transamidase; glutamine-oxo acid aminotransferase

Systematic name: L-glutamine:pyruvate aminotransferase

Comments: A pyridoxal-phosphate protein. L-Methionine can act as donor; glyoxylate can act as acceptor.

Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, PDB, CAS registry number: 9030-44-8

References:

1. Cooper, A.J.L. and Meister, A. Isolation and properties of highly purified glutamine transaminase. Biochemistry 11 (1972) 661-671. [PMID: 5059882]

2. Meister, A. Studies on the mechanism and specificity of the glutamine-α-keto acid transamination-deamidation reaction. J. Biol. Chem. 210 (1954) 17-35.

[EC 2.6.1.15 created 1961]


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