IUBMB Enzyme Nomenclature


Accepted name: tryptophan—phenylpyruvate transaminase

Reaction: L-tryptophan + phenylpyruvate = (indol-3-yl)pyruvate + L-phenylalanine

For diagram click here (mechanism).

Other name(s): L-tryptophan-α-ketoisocaproate aminotransferase

Systematic name: L-tryptophan:phenylpyruvate aminotransferase

Comments: Valine, leucine and isoleucine can replace tryptophan as amino donor.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37277-87-5


1. Koide, Y., Honma, M. and Shimomura, T. L-Tryptophan-α-ketoisocaproate aminotransferase from Pseudomonas sp. Agric. Biol. Chem. 44 (1980) 2013-2019.

2. Sukanya, N.K.and Vaidyanathan, C.S. Aminotransferases of Agrobacterium tumefaciens. Transamination between tryptophan and phenylpyruvate. Biochem. J. 92 (1964) 594-598. [PMID: 5837443]

[EC created 1972]

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