Reaction: dTDP-4-amino-4,6-dideoxy-α-D-glucose + 2-oxoglutarate = dTDP-4-dehydro-6-deoxy-α-D-glucose + L-glutamate
For diagram of reaction click here.
Other name(s): thymidine diphospho-4-amino-4,6-dideoxyglucose aminotransferase; thymidine diphospho-4-amino-6-deoxyglucose aminotransferase; thymidine diphospho-4-keto-6-deoxy-D-glucose transaminase; thymidine diphospho-4-keto-6-deoxy-D-glucose-glutamic transaminase; TDP-4-keto-6-deoxy-D-glucose transaminase; dTDP-4-amino-4,6-dideoxy-α-D-glucose:2-oxoglutarate aminotransferase
Systematic name: dTDP-4-amino-4,6-dideoxy-α-D-glucose:2-oxoglutarate aminotransferase
Comments: A pyridoxal-phosphate protein.
Links to other databases: BRENDA, EXPASY, GTD, KEGG, Metacyc, CAS registry number: 9023-19-2
References:
1. Matsuhashi, M. and Strominger, J.L. Thymidine diphosphate 4-acetamido-2,6-dideoxyhexoses. 3. Purification and properties of thymidine diphosphate 4-keto-6-deoxy-D-glucose transaminase from Escherichia coli strain B. J. Biol. Chem. 241 (1966) 4738-4744. [PMID: 5332731]
2. Wang, Y., Xu, Y., Perepelov, A.V., Qi, Y., Knirel, Y.A., Wang, L. and Feng, L. Biochemical characterization of dTDP-D-Qui4N and dTDP-D-Qui4NAc biosynthetic pathways in Shigella dysenteriae type 7 and Escherichia coli O7. J. Bacteriol. 189 (2007) 8626-8635. [PMID: 17905981]