IUBMB Enzyme Nomenclature


Accepted name: (R)-3-amino-2-methylpropionate—pyruvate transaminase

Reaction: (R)-3-amino-2-methylpropanoate + pyruvate = 2-methyl-3-oxopropanoate + L-alanine

For diagram click here.

Other name(s): D-3-aminoisobutyrate—pyruvate transaminase; β-aminoisobutyrate-pyruvate aminotransferase; D-3-aminoisobutyrate-pyruvate aminotransferase; D-3-aminoisobutyrate-pyruvate transaminase; (R)-3-amino-2-methylpropionate transaminase; D-β-aminoisobutyrate:pyruvate aminotransferase

Systematic name: (R)-3-amino-2-methylpropanoate:pyruvate aminotransferase

Comments: The two enantiomers of the 2-methyl-3-oxopropanoate formed by the enzyme interconvert by enolization, so that this enzyme, together with EC, (S)-3-amino-2-methylpropionate transaminase, provide a route for interconversion of the enantiomers of 3-amino-2-methylpropanoate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 37279-00-8


1. Kakimoto, Y., Taniguchi, K. and Sano, I. D-β-Aminoisobutyrate:pyruvate aminotransferase in mammalian liver and excretion of β-aminoisobutyrate by man. J. Biol. Chem. 244 (1969) 335-340. [PMID: 5773299]

2. Tamaki, N., Sakata, S.F. and Matsuda, K. Purification, properties, and sequencing of aminoisobutyrate aminotransferases from rat liver. Methods Enzymol. 324 (2000) 376-389. [PMID: 10989446]

[EC created 1972 (EC created 1982, incorporated 2004) modified 2004]

Return to EC 2.6.1 home page
Return to EC 2.6 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page