Reaction: 5-aminolevulinate + pyruvate = 4,5-dioxopentanoate + L-alanine
Other name(s): aminolevulinate aminotransferase; γ,δ-dioxovalerate aminotransferase; γ,δ-dioxovaleric acid transaminase; 4,5-dioxovalerate aminotransferase; 4,5-dioxovaleric acid transaminase; 4,5-dioxovaleric transaminase; 5-aminolevulinic acid transaminase; alanine-γ,δ-dioxovalerate aminotransferase; alanine-dioxovalerate aminotransferase; alanine:4,5-dioxovalerate aminotransferase; aminolevulinic acid transaminase; dioxovalerate transaminase; L-alanine-4,5-dioxovalerate aminotransferase; L-alanine:4,5-dioxovaleric acid transaminase; L-alanine:dioxovalerate transaminase; DOVA transaminase; 4,5-dioxovaleric acid aminotransferase
Systematic name: 5-aminolevulinate:pyruvate aminotransferase
Comments: A pyridoxal-phosphate protein.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9012-46-8
References:
1. Gibson, K.D., Matthew, M. and Neuberger, A. Biosynthesis of porphyrins and chlorophylls. Nature 192 (1961) 204-208.
2. Neuberger, A. and Turner, J.M. γ,δ-Dioxovalerate aminotransferase activity in Rhodopseudomonas spheroides. Biochim. Biophys. Acta 67 (1963) 342-345.