IUBMB Enzyme Nomenclature


Accepted name: phenylalanine(histidine) transaminase

Reaction: L-phenylalanine + pyruvate = phenylpyruvate + L-alanine

For diagram click here (mechanism).

Other name(s): phenylalanine (histidine) aminotransferase; phenylalanine(histidine):pyruvate aminotransferase; histidine:pyruvate aminotransferase; L-phenylalanine(L-histidine):pyruvate aminotransferase

Systematic name: L-phenylalanine:pyruvate aminotransferase

Comments: L-Histidine and L-tyrosine can act instead of L-phenylalanine; in the reverse reaction, L-methionine, L-serine and L-glutamine can replace L-alanine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 72560-98-6


1. Minatogawa, Y., Noguchi, T. and Kido, R. Species distribution and properties of hepatic phenylalanine (histidine):pyruvate aminotransferase. Hoppe-Seyler's Z. Physiol. Chem. 358 (1977) 59-67. [PMID: 14070]

[EC created 1978]

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