IUBMB Enzyme Nomenclature


Accepted name: cephalosporin-C transaminase

Reaction: (7R)-7-(5-carboxy-5-oxopentanoyl)aminocephalosporinate + D-glutamate = cephalosporin C + 2-oxoglutarate

For diagram click here.

Glossary: cephalosporin C = (7R)-7-(5-carboxy-5-oxopentanamido)cephalosporanate

Other name(s): cephalosporin C aminotransferase; L-alanine:cephalosporin-C aminotransferase

Systematic name: cephalosporin-C:2-oxoglutarate aminotransferase

Comments: A number of D-amino acids, including D-alanine, D-aspartate and D-methionine can also act as amino-group donors. Although this enzyme acts on several free D-amino acids, it differs from EC, D-alanine transaminase, in that it can use cephalosporin C as an amino donor.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 122096-91-7


1. Aretz, W. and Sauber, K. Novel D-amino acid transaminase. Ann. N.Y. Acad. Sci. 542 (1988) 366-370. [PMID: 3228235]

[EC created 1992, modified 2005]

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