IUBMB Enzyme Nomenclature

EC 2.7.7.71

Accepted name: D-glycero-α-D-manno-heptose 1-phosphate guanylyltransferase

Reaction: D-glycero-α-D-manno-heptose 1-phosphate + GTP = GDP-D-glycero-α-D-manno-heptose + diphosphate

Other name(s): hddC (gene name); gmhD (gene name)

Systematic name: GTP:D-glycero-α-D-manno-heptose 1-phosphate guanylyltransferase

Comments: The enzyme is involved in biosynthesis of GDP-D-glycero-α-D-manno-heptose, which is required for assembly of S-layer glycoprotein in some Gram-positive bacteria.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number:

References:

1. Kneidinger, B., Graninger, M., Puchberger, M., Kosma, P. and Messner, P. Biosynthesis of nucleotide-activated D-glycero-D-manno-heptose. J. Biol. Chem. 276 (2001) 20935-20944. [PMID: 11279237]

[EC 2.7.7.71 created 2010]


Return to EC 2.7.7 home page
Return to EC 2.7 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page