IUBMB Enzyme Nomenclature


Accepted name: thiol sulfotransferase

Reaction: 3'-phosphoadenylyl sulfate + a thiol = adenosine 3',5'-bisphosphate + an S-alkyl thiosulfate

Glossary: 3'-phosphoadenylyl sulfate = PAPS

Other names: phosphoadenylylsulfate-thiol sulfotransferase; PAPS sulfotransferase; adenosine 3'-phosphate 5'-sulphatophosphate sulfotransferase; 3'-phosphoadenylyl-sulfate:thiol S-sulfotransferase

Systematic name: 3'-phosphoadenylyl-sulfate:thiol S-sulfonotransferase

Comments: Also acts on dithiols; substrates include glutathione, dithioerythritol and 2,3-bis(sulfanyl)propan-1-ol..

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 70356-45-5


1. Schmidt, A. The adenosine-5'-phosphosulfate sulfotransferase from spinach (Spinacea oleracea L.). Stabilization, partial purification, and properties. Planta 130 (1976) 257-263.

2. Schmidt, A. and Christen, U. A PAPS-dependent sulfotransferase in Cyanophora paradoxa inhibited by 5'-AMP, 5'-ADP and APS. Z. Naturforsch. C: Biosci. 34 (1979) 222-228.

3. Tsang, M. L.-S. and Schiff, J.A. Studies of sulfate utilization by algae. 17. Reactions of the adenosine 5'-phosphosulfate (APS) sulfotransferase from Chlorella and studies of model reactions which explain the diversity of side products with thiols. Plant Cell Physiol. 17 (1976) 1209-1220.

[EC created 1984]

Return to EC 2.8.2 home page
Return to EC 2.8 home page
Return to EC 2 home page
Return to Enzymes home page
Return to IUBMB Biochemical Nomenclature home page