Reaction: 3'-phosphoadenylyl sulfate + cortisol = adenosine 3',5'-bisphosphate + cortisol 21-sulfate
Glossary: 3'-phosphoadenylyl sulfate = PAPS
Other name(s): glucocorticosteroid sulfotransferase; glucocorticoid sulfotransferase; 3'-phosphoadenylyl-sulfate:cortisol 21-sulfotransferase
Systematic name: 3'-phosphoadenylyl-sulfate:cortisol 21-sulfonotransferase
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 59782-20-6
References:
1. Singer, S.S. and Brill, B. Enzymatic sulfation of steroids. XVII. The properties of the glucocorticoid sulfotransferase activity of guinea pig liver cytosol. Biochim. Biophys. Acta 712 (1982) 590-596. [PMID: 6957246]
2. Singer, S.S., Giera, D., Johnson, J. and Sylvester, S. Enzymatic sulfation of steroids: I. The enzymatic basis for the sex difference in cortisol sulfation by rat liver preparations. Endocrinology 98 (1976) 963-974. [PMID: 1278101]