IUBMB Enzyme Nomenclature


Accepted name: protein-tyrosine sulfotransferase

Reaction: 3'-phosphoadenylyl sulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate

Glossary: 3'-phosphoadenylyl sulfate = PAPS

Other name(s): tyrosylprotein sulfotransferase; 3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfotransferase

Systematic name: 3'-phosphoadenylyl-sulfate:protein-tyrosine O-sulfonotransferase

Comments: The tyrosine residues of some specific proteins of rat pheochromocytoma cells act as acceptors.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 87588-33-8


1. Lee, R.W.H. and Huttner, W.B. Tyrosine-O-sulfated proteins of PC12 pheochromocytoma cells and their sulfation by a tyrosylprotein sulfotransferase. J. Biol. Chem. 258 (1983) 11326-11334. [PMID: 6577005]

[EC created 1986]

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