IUBMB Enzyme Nomenclature


Accepted name: amine sulfotransferase

Reaction: 3'-phosphoadenylyl sulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate

Glossary: 3'-phosphoadenylyl sulfate = PAPS

Other name(s): arylamine sulfotransferase; amine N-sulfotransferase; 3'-phosphoadenylyl-sulfate:amine N-sulfotransferase

Systematic name: 3'-phosphoadenylyl-sulfate:amine N-sulfonotransferase

Comments: A large number of primary and secondary amines can act as acceptors, including aniline, 2-naphthylamine, cyclohexylamine and octylamine.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9026-08-8


1. Ramaswamy, S.G. and Jakoby, W.B. Amine N-sulfotransferase. J. Biol. Chem. 262 (1987) 10039-10043. [PMID: 3475273]

2. Roy, A.B. The enzymic synthesis of aryl sulphamates. Biochem. J. 74 (1960) 49-56.

[EC created 1965]

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