Reaction: 3'-phosphoadenylyl sulfate + an amine = adenosine 3',5'-bisphosphate + a sulfamate
Glossary: 3'-phosphoadenylyl sulfate = PAPS
Other name(s): arylamine sulfotransferase; amine N-sulfotransferase; 3'-phosphoadenylyl-sulfate:amine N-sulfotransferase
Systematic name: 3'-phosphoadenylyl-sulfate:amine N-sulfonotransferase
Comments: A large number of primary and secondary amines can act as acceptors, including aniline, 2-naphthylamine, cyclohexylamine and octylamine.
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, PDB, CAS registry number: 9026-08-8
1. Ramaswamy, S.G. and Jakoby, W.B. Amine N-sulfotransferase. J. Biol. Chem. 262 (1987) 10039-10043. [PMID: 3475273]
2. Roy, A.B. The enzymic synthesis of aryl sulphamates. Biochem. J. 74 (1960) 49-56.