IUBMB Enzyme Nomenclature


Accepted name: tyrosine-ester sulfotransferase

Reaction: 3'-phosphoadenylyl sulfate + L-tyrosine methyl ester = adenosine 3',5'-bisphosphate + L-tyrosine methyl ester 4-sulfate

Glossary: 3'-phosphoadenylyl sulfate = PAPS

Other names: aryl sulfotransferase IV; L-tyrosine methyl ester sulfotransferase; 3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase

Systematic name: 3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfonotransferase

Comments: Phenols and organic hydroxylamines can act as acceptors (cf. EC aryl sulfotransferase).

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9055-56-5


1. Duffel, M. and Jakoby, W.B. On the mechanism of aryl sulfotransferase. J. Biol. Chem. 256 (1981) 11123-111277. [PMID: 6945304]

2. Mattock, P. and Jones, J.G. Partial purification and properties of an enzyme from rat liver that catalyses the sulphation of L-tyrosyl derivatives. Biochem. J. 116 (1970) 797-803. [PMID: 5441369]

3. Sekura, R. and Jakoby, W.B. Aryl sulfotransferase IV from rat liver. Arch. Biochem. Biophys. 211 (1981) 352-359. [PMID: 6946725]

[EC created 1972, deleted 1980, reinstated 1984]

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