Reaction: 3'-phosphoadenylyl sulfate + L-tyrosine methyl ester = adenosine 3',5'-bisphosphate + L-tyrosine methyl ester 4-sulfate
Glossary: 3'-phosphoadenylyl sulfate = PAPS
Other names: aryl sulfotransferase IV; L-tyrosine methyl ester sulfotransferase; 3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfotransferase
Systematic name: 3'-phosphoadenylyl-sulfate:L-tyrosine-methyl-ester sulfonotransferase
Comments: Phenols and organic hydroxylamines can act as acceptors (cf. EC 2.8.2.1 aryl sulfotransferase).
Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 9055-56-5
References:
1. Duffel, M. and Jakoby, W.B. On the mechanism of aryl sulfotransferase. J. Biol. Chem. 256 (1981) 11123-111277. [PMID: 6945304]
2. Mattock, P. and Jones, J.G. Partial purification and properties of an enzyme from rat liver that catalyses the sulphation of L-tyrosyl derivatives. Biochem. J. 116 (1970) 797-803. [PMID: 5441369]
3. Sekura, R. and Jakoby, W.B. Aryl sulfotransferase IV from rat liver. Arch. Biochem. Biophys. 211 (1981) 352-359. [PMID: 6946725]