IUBMB Enzyme Nomenclature

EC 2.8.3.14

Accepted name: 5-hydroxypentanoate CoA-transferase

Reaction: acetyl-CoA + 5-hydroxypentanoate = acetate + 5-hydroxypentanoyl-CoA

Other name(s): 5-hydroxyvalerate CoA-transferase; 5-hydroxyvalerate coenzyme A transferase

Systematic name: acetyl-CoA:5-hydroxypentanoate CoA-transferase

Comments: Propanoyl-CoA, acetyl-CoA, butanoyl-CoA and some other acyl-CoAs can act as substrates, but more slowly than 5-hydroxypentanoyl-CoA.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 111684-68-5

References:

1. Eikmanns, U. and Buckel, W. Properties of 5-hydroxyvalerate CoA-transferase from Clostridium aminovalericum. Biol. Chem. Hoppe-Seyler 371 (1990) 1077-1082. [PMID: 2085413]

[EC 2.8.3.14 created 1992]


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