IUBMB Enzyme Nomenclature


Accepted name: succinyl-CoA—D-citramalate CoA-transferase

Reaction: (1) succinyl-CoA + (R)-citramalate = succinate + (R)-citramalyl-CoA
(2) succinyl-CoA + (R)-malate = succinate + (R)-malyl-CoA

Glossary: (R)-citramalate = (2R)-2-hydroxy-2-methylbutanedioate
(R)-malate = (2R)-2-hydroxybutanedioate
(R)-malyl-CoA = (3R)-3-carboxy-3-hydroxypropanoyl-CoA

Other name(s): Sct

Systematic name: succinyl-CoA:(R)-citramalate CoA-transferase

Comments: The enzyme, purified from the bacterium Clostridium tetanomorphum, can also accept itaconate as acceptor, with lower efficiency.

Links to other databases: BRENDA, EXPASY, KEGG, MetaCyc, CAS registry number:


1. Friedmann, S., Alber, B.E. and Fuchs, G. Properties of succinyl-coenzyme A:D-citramalate coenzyme A transferase and its role in the autotrophic 3-hydroxypropionate cycle of Chloroflexus aurantiacus. J. Bacteriol. 188 (2006) 6460-6468. [PMID: 16952935]

[EC created 2014]

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