IUBMB Enzyme Nomenclature

EC 2.8.3.6

Accepted name: 3-oxoadipate CoA-transferase

Reaction: succinyl-CoA + 3-oxoadipate = succinate + 3-oxoadipyl-CoA

For diagram click here or click here.

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Other names: 3-oxoadipate coenzyme A-transferase; 3-oxoadipate succinyl-CoA transferase

Systematic name: succinyl-CoA:3-oxoadipate CoA-transferase

Comments: The enzyme, often found in soil bacteria and fungi, is involved in the catabolism of a variety of aromatic compounds, including catechol and protocatechuate, which are degraded via 3-oxoadipate.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, UM-BBD, CAS registry number: 9026-16-8

References:

1. Katagiri, M. and Hayaishi, O. Enzymatic degradation of β-ketoadipic acid. J. Biol. Chem. 226 (1957) 439-448.

2. Kaschabek, S.R., Kuhn, B., Müller, D., Schmidt, E. and Reineke, W. Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: purification and characterization of 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase. J. Bacteriol. 184 (2002) 207–215. [PMID: 11741862]

3. Gobel, M., Kassel-Cati, K., Schmidt, E. and Reineke, W. Degradation of aromatics and chloroaromatics by Pseudomonas sp. strain B13: cloning, characterization, and analysis of sequences encoding 3-oxoadipate:succinyl-coenzyme A (CoA) transferase and 3-oxoadipyl-CoA thiolase. J. Bacteriol. 184 (2002) 216–223. [PMID: 11741863]

[EC 2.8.3.6 created 1961]


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