IUBMB Enzyme Nomenclature


Accepted name: butyrate—acetoacetate CoA-transferase

Reaction: butanoyl-CoA + acetoacetate = butanoate + acetoacetyl-CoA

Other names: butyryl coenzyme A-acetoacetate coenzyme A-transferase; butyryl-CoA-acetoacetate CoA-transferase

Systematic name: butanoyl-CoA:acetoacetate CoA-transferase

Comments: Butanoate, acetoacetate and their CoA thioesters are the preferred substrates, but the enzyme also acts, more slowly, on the derivatives of a number of C2 to C6 monocarboxylic acids.

Links to other databases: BRENDA, EXPASY, KEGG, Metacyc, CAS registry number: 66231-37-6


1. Barker, H.A., Jeng, I.-M., Neff, N., Robertson, J.M., Tam, F.K. and Hosaka, S. Butyryl-CoA:acetoacetate CoA-transferase from a lysine-fermenting Clostridium. J. Biol. Chem. 253 (1978) 1219-1225. [PMID: 624727]

[EC created 1984]

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